Peer-Reviewed
Articles
A
Meta-Analysis of the MCG clinical trials
International Journal of Medical Sciences April
2009 6(4):143-155
An
analysis of the Asian Multi-Center Trial
Congestive Heart Failure 2008 14: 251-260
An
analysis of the Siegburg clinical trial (post-revascularization)
International Journal of Medical Sciences 2008
5(2): 50-61
An
analysis of the Siegburg clinical trial (no revascularization)
International Journal of Medical Sciences 2007
4(5): 249-263
An
analysis of the Westchester clinical trial
Heart Disease 2002 4: 2-1
ASCVD
Progression (video)
Peer-Reviewed Abstracts and Presentations
An analysis of the effect
of age, gender and revascularization on MCG results
(Based upon the Siegburg studies)
Circulation 2007 116: II_367
Abstract
| Presentation
Slides
A comparison of the MCG system to coronary angiography
(Based upon the Post-Revascularization Siegburg study)
American College of Chest Physicians October 2007
132(4): 466S
Abstract
| Presentation
Slides
Invited Talks
American Academy of Urgent Care
Medicine
Drs. Imhoff, Strobeck and Shen discuss the MCG system,
including trial results, practical clinical examples and
the underlying technology.
A presentation before the Academy's 2008 annual meeting
Presentation
Video
Premier Heart's MCG system is founded
on the principles of evidence-based medicine. As such,
we believe that the best way of demonstrating the accuracy
and capabilities of our technology is through well designed
double-blind clinical trials coupled with ongoing analysis
and review of our system's performance in daily clinical
practice.
This page presents an overview of our peer-reviewed
clinical trial results. It includes summary data for each
trial as well as electronic copies of the peer-reviewed
articles detailing the methods used in each study.
If you have questions or would like more
information on any of the trials listed below please feel
free to contact
us.
Summary Data: Clinical Trials
2000 - 2004
This summary includes statistical
information from our clinical trials between 2000 and
2004, representing a sample of over 1,000 patients in
three major geographic regions (North America, Europe
and Asia).
All studies in this group were performed in accordance
with MCG's Westchester Study Protocol, utilizing
standard double-blind testing and independent verification
of results.
Overall sensitivity across these studies was 91% (specificity
83.8%, positive predictive value 77.6%, negative predictive
value 92.4%).
Meta
Analysis Article - Published in the International
Journal of Medical Sciences 2009; 6(4) pp 143-144.
The trials below were conducted
with our first generation MCG and MCG/mfEMT software
suite - MCG shares the underlying diagnostic technology
and produces identical results.
Westchester Medical
Center - New York, USA
| Trial
Article |
This study compared the results
from MCG with the results of coronary angiograms
in a random sample of 136 patients.
This study showed a sensitivity of 93.3% (specificity
83%, positive predictive value 91.2%, negative
predictive value 86.7%).
|
Results were published in Heart
Disease 2002; 4: pp 2-12. |
Siegburg Heart Center
- Siegburg, Germany
Two studies were performed at the Siegburg heart
center in Siegburg, Germany, evaluating MCG in patient
populations with and without a history of revascularization.
Trial
Article
Monitor
Letter |
The first study evaluated
the use of MCG in a set of 423 patients with
no prior history of coronary revascularization.
In this study our technology showed a sensitivity
of 89.1% (specificity 81.1%, positive predictive
value 79%, negative predictive value 90%).
|
Results were published in International
Journal of Medical Sciences 2007 4(5): pp 249-263.
Trial
Article
Monitor
Letter |
The second study evaluated
the ability of our technology to deal with
the special challenges of patients with a
prior history of coronary revascularization,
testing in a sample of 172 patients.
In this study our technology showed a sensitivity
of 90.9% (specificity 88%, positive predictive
value 62.7%, negative predictive value 97.8%).
|
Results were published in International
Journal of Medical Sciences 2008 5(2): pp 50-61.
|
Asian Multicenter
- Four sites
Trial
Article
Monitor
Letter |
This study was conducted across
four centers in Asia with a sample of 189
patients (including patients with and without
a history of prior revascularization).
This study yielded a sensitivity of 94.8%
(specificity 86.6%, positive predictive value
78.4%, negative predictive value 97.1%).
|
Results were published in Congestive
Heart Failure 2008 14: pp. 251-260 |
|
